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LEADER 04019cam 2200529 i 4500
001
ocn958371110
003
OCoLC
005
20170725092334.0
008
160908t20172017nyu b 001 0 eng
010
a| 2016024105
019
a| 957133460
020
a| 9780190651244 (hardback : acid-free paper)
020
a| 0190651245 (hardback : acid-free paper)
020
z| 9780190651268 (ebook)
020
z| 9780190651275 (online resource)
035
a| (Sirsi) 40027102100
035
a| 40027102100
035
a| (OCoLC)958371110
z| (OCoLC)957133460
040
a| DLC
b| eng
e| rda
c| DLC
d| YDX
d| OCLCF
d| LSH
d| NRC
d| UtOrBLW
042
a| pcc
050
0
0
a| QR181
b| .T37 2017
082
0
0
a| 616.07/9
2| 23
084
a| SCI075000
a| MED044000
2| bisacsh
100
1
a| Tauber, Alfred I.
=| ^A232171
245
1
0
a| Immunity :
b| the evolution of an idea /
c| Alfred I. Tauber.
264
1
a| New York, NY, United States of America :
b| Oxford University Press,
c| [2017]
264
4
c| ©2017
300
a| xx, 303 pages ;
c| 25 cm
336
a| text
b| txt
2| rdacontent
337
a| unmediated
b| n
2| rdamedia
338
a| volume
b| nc
2| rdacarrier
520
a| " Senior scholar Alfred Tauber argues in this bold account that common approaches to the study of immunology are inherently flawed in its strict dichotomy of the self and non-self, or external invaders. The relationship between what is self and what is non-self is in reality a complex, dymanic, relational one. Autonomous agents are constantly in the midst of dialectical exchanges in which immunity mediates both noxious and benign encounters. Namely: rather than serving to defend an independent entity, immunity participates in an eco-system. Contemporary transplantation biology and autoimmunity have demonstrated phenomena that upset rigid adherence to the self/non-self dichotomy. Placing tolerant immune mechanisms within a broad ecological context has highlighted the balance of co-operative and competitive relationships in which immunity functions. By understanding immunity this way, as a 'symbiotic turn,' we come to see that immune reactivity (rejection or tolerance) is a second-order response to the cognitive functions of the immune system. Organisms have a complex capacity to respond to environment, and, through Tauber's insignts, we appreciate them more fully when we grasp the flexibility of the borders of organisms. After first providing an overview of the history of immunology, and explaining why the dominant understanding of it is incomplete and limiting, Tauber argues for this new approach to immunology and explains how it will usher in a new biology in which symbiosis is the rule, not the exception. "--
c| Provided by publisher.
520
a| "Immunity mediates both defensive and cooperative relations with the environment. Therefore, the traditional focus on host defense misconstrues the full spectrum of immune activities. An alternate model based on immune balance highlights the information processing of immune perception that precedes discriminatory decisions -- to reject, assimilate, or ignore the identified object"--
c| Provided by publisher.
504
a| Includes bibliographical references and index.
505
8
a| Chapter 1: A History of the Immune Self -- Chapter 2: Whither Immune Identity? -- Chapter 3: Individuality Revised -- Chapter 4: Immune Cognition -- Chapter 5: Eco-immunology -- Chapter 6: A New Biology?
650
0
a| Immunology
x| Philosophy.
=| ^A105463
650
7
a| SCIENCE / Philosophy & Social Aspects.
2| bisacsh
650
7
a| MEDICAL / Immunology.
2| bisacsh
650
7
a| Immunology
x| Philosophy.
2| fast
0| (OCoLC)fst00968021
650
4
a| SCIENCE / Philosophy & Social Aspects.
650
4
a| Clinical immunology.
650
4
a| Immunology
x| Philosophy.
949
i| 30372016639889
o| jjlm
960
o| 1
s| 74.00
t| Joyner48
u| JAPP
z| USD
596
a| 1
998
a| 4696311
999
a| QR181 .T37 2017
w| LC
c| 1
i| 30372016639889
d| 12/21/2017
e| 5/25/2017
l| JGES
m| JOYNER
r| Y
s| Y
t| JGESBK
u| 5/16/2017
x| BOOK
z| JSTACKS
o| .STAFF. jjlm