An introduction to statistics in early phase trials

An introduction to statistics in early phase trials / Steven A. Julious, Say Beng Tan, David Machin.

Author/creator	Julious, Steven A.
Other author/creator	Machin, David, 1939-
Other author/creator	Tan, Say Beng.
Format	Electronic and Book
Publication Info	The Atrium, Southern Gate, Chichester, West Sussex, UK ; Hoboken, NJ : Wiley-Blackwell,
Description	263 p. : ill. ; 26 cm.
Supplemental Content	Full text available from Ebook Central - Academic Complete
Subject(s)	Drugs--Testing --Statistical methods. Clinical trials--Statistical methods. Clinical Trials, Phase I as Topic--methods. Biometry--methods. Clinical Trials, Phase II as Topic--methods. Models, Statistical. Statistics as Topic--methods.

Contents	Early phase trials -- Introduction to pharmacokinetics -- Sample size calculations for clinical trials -- Crossover trial basics -- Multi-period crossover trials -- First time into man -- Bayesian and frequentist methods -- First-time-into-new-population studies -- Bioequivalence studies -- Other phase I trials -- Phase II trials : general issues -- Dose-response studies -- Phase II trials with toxic therapies -- Interpreting and applying early phase trial results -- Go/no-go criteria.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2009033763
ISBN	9780470059852
ISBN	0470059850

Library	Location	Call Number	Status	Item Actions
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