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LEADER 04178cam 2200481 a 4500
001
ssj0000633087
003
WaSeSS
005
20200412081236.0
006
m d
007
cr n
008
110927s2012 njua sb 001 0 eng d
010
a| 2011040165
020
a| 9780470601815 (cloth)
020
a| 0470601817 (cloth)
035
a| (WaSeSS)ssj0000633087
040
a| DNLM/DLC
c| DLC
d| DLC
d| WaSeSS
042
a| pcc
049
a| EREE
a| NEHH
050
0
0
a| RM301.25
b| .C37 2012
060
1
0
a| QV 744
082
0
0
a| 615.19
2| 23
245
0
0
a| Case studies in modern drug discovery and development
h| [electronic resource] /
c| edited by Xianhai Huang, Robert G. Aslanian.
260
a| Hoboken, New Jersey :
b| Wiley,
300
a| xviii, 451 p. :
b| ill. ;
c| 26 cm.
504
a| Includes bibliographical references and index.
505
0
a| Introduction: drug discovery in difficult times / Malcom MacCoss -- Discovery and development of the DPP-4 inhibitor JANUVIA? (Sitagliptin) / Emma R. Parmee ... [et al.] -- Olmesartan medoxiomil, an angiotensin II receptor blocker / Hiroaki Yanagisawa, Hiroyuki Koike, and Shinichiro Miura -- Discovery of heterocyclic phosphonic acids as novel AMP mimics that are potent and selective fructose-1,6-bisphosphatase inhibitors and elicit potent glucose-lowering effects in diabetic animals and human / Qun Dang, and Mark D. Erion -- Setting the paradigm of targeted drugs for the treatment of cancer : Imatinib and Nilotinib therapies for chronic myelogenous leukaemia / Paul W. Manley and Jürg Zimmermann -- Amrubicin, a completely synthetic 9-aminoanthracycline, for extensive-disease small-cell lung cancer / Mitsuharu Hanada -- The discovery of dual IGF-1R and IR inhibitor FQIT for the treatment of cancer / Meizhong Jin, Elizabeth Buck, and Mark J. Mulvihill -- Discovery and development of Montelukast (Singulair?) / Robert N. Young -- Discovery and development of Maraviroc, a CCR5 antagonist for the treatment of HIV Infection / Patrick Dorr, Blanda Stammen, Elna van der Ryst -- Discovery of antimalarial drug Artemisinin and beyond / Ao Zhang, Weiwei Mao, Yu Zhang -- Discovery and process development of MK-4965, a potent non-nucleoside reverse transcriptase inhibitor / Yong-Li Zhong, Thomas J. Tucker, and Jingjun Yin -- Discovery of Boceprevir and Narlaprevir : the first and second generation of HCV NS3 protease inhibitors / Kevin X. Chen, F. George Njoroge -- The discovery of Samsca (Tolvaptan) : the first oral nonpeptide vasopressin receptor antagonist / Kazumi Kondo, Yoshitaka Yamamura -- SILODOSIN (Urief?, Rapaflo?, Thrupas?, Urorec?, SilodixTM) : a selective à1A adrenoceptor antagonist for the treatment of benign prostatic hyperplasia / Masaki Yoshida ... [et al.] -- Raloxifene : a selective estrogen receptor modulator (SERM) / Jeffrey A. Dodge and Henry U. Bryant.
506
a| Available only to authorized users.
538
a| Mode of access: World Wide Web
650
1
2
a| Drug Discovery.
=| ^A1013013
650
2
2
a| Drug Evaluation.
=| ^A917639
655
0
a| Electronic books.
=| ^A491897
700
1
a| Huang, Xianhai.
?| UNAUTHORIZED
700
1
a| Aslanian, Robert G.
?| UNAUTHORIZED
856
4
0
z| Full text available from Books@Ovid - Wiley Essentials in Pharmaceutical Science Book Collection
u| https://go.openathens.net/redirector/ecu.edu?url=http%3A%2F%2Fovidsp.ovid.com%2Fovidweb.cgi%3FT%3DJS%26NEWS%3Dn%26CSC%3DY%26PAGE%3Dbooktext%26D%3Dbooks%26AN%3D01741016%24%26XPATH%3D%2FPG%280%29
856
4
0
z| Full text available from Ebook Central - Academic Complete
u| https://ebookcentral.proquest.com/lib/eastcarolina/detail.action?docID=822083
949
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949
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